G-protein coupled receptors (GPCRs) are popular biological targets for drug discovery and development.To date there are more than 140 orphan GPCRs, i.e.receptors whose endogenous ligands are unknown.Traditionally orphan GPCRs have been difficult to study and the development of therapeutic compounds targeting these receptors has been extremely slow

Internationalisation has been a key theme in higher education (HE) for decades.Multiple initiatives across the world have VISION FACTORS contributed to creating offerings of high-quality online education, with collaborations across national borders.Two of the concepts that have proved to be influential are Virtual Mobility (VM) and Open Education (

Protected Areas (PAs) in Bangladesh have been pivotal for conserving wildlife.The country plans to increase the number of PAs by implementing new forest-governing policies with the involvement of local communities.Their efficacy in wildlife conservation and forest preservation is being questioned due to significant land cover changes within PA boun

Information protection is an important safety issue in many human activity fields.Technological advances and related ubiquitous computerization bring new challenges in this area.In particular, the problem concerns the protection of devices against non-invasive acquisition processed information in ICT systems.It is known that, e.g., VGA, DVI/HDMI in

Abstract Vortex reconnections are ubiquitous events found in diverse media.Here we show that vortex reconnections also occur Cardigans between spatiotemporal vortices in optical waves.Since vortices exhibit orbital angular momentum (OAM), the reconnections of optical vortices create a variety of connected OAM states.Dispersion and diffraction can c